中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (34): 6445-6448.doi: 10.3969/j.issn. 2095-4344.2012.34. 035

• 组织构建临床实践 clinical practice in tissue construction • 上一篇    下一篇

逆行性人工鼻泪管植入修复泪道阻塞性疾病：18个月随访

何 跃，张熙伯，吕红彬，欧阳科   

  1. 泸州医学院附属医院眼科，四川省泸州市 646000
  • 收稿日期:2011-11-08 修回日期:2012-01-30 出版日期:2012-08-19 发布日期:2012-08-19
  • 通讯作者: 张熙伯，副教授，泸州医学院附属医院眼科，四川省泸州市 646000
  • 作者简介:何跃★，男，1978年生，四川省南充市人，汉族，2010年昆明医学院毕业，硕士，主治医师，主要从事眼底疾病、青光眼、泪道方面研究

Retrograde nasolacrimal duct implantation for the treatment of nasolacrimal duct obstruction

He Yue, Zhang Xi-bo, Lü Hong-bin, Ouyang Ke   

  1. Department of Ophthalmology, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China
  • Received:2011-11-08 Revised:2012-01-30 Online:2012-08-19 Published:2012-08-19
  • Contact: Zhang Xi-bo, Associate professor, Department of Ophthalmology, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China
  • About author:He Yue★, Master, Attending physician, Department of Ophthalmology, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China hylyfy@163.com

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摘要：

背景：人工鼻泪管植入治疗泪道阻塞性疾病不会改变泪道的解剖结构，是一种简单有效的治疗方法。
目的：评价人工鼻泪管植入治疗泪道阻塞性疾病的有效性及安全性。
方法：选择2008/2009逆行性人工鼻泪管植入治疗泪道阻塞患者87例，共94眼，年龄26~71岁，平均56岁。其中鼻泪管阻塞患者31例，慢性泪囊炎患者56例。随访时间为18个月。
结果与结论：人工鼻泪管植入后第2天92眼溢泪症状完全缓解，成功率为98% (92/94)。随访中，85眼人工鼻泪管保持通畅，8眼发生阻塞，1眼发生人工鼻泪管移位，植入有效率为90%(85/94)。植入后有7例患者出现疼痛，2例出现眼睑水肿，所有患者均有少量鼻出血，经对症处理后均缓解。结果可见人工鼻泪管植入是治疗泪道阻塞性疾病简单有效安全的方法。

关键词: 人工鼻泪管, 溢泪, 泪道阻塞, 慢性泪囊炎, 泪道系统治疗

Abstract:

BACKGROUND: Polyurethane nasolacrimal duct stents cannot alter the anatomical structure of lacrimal outflow pathway and is a quick and useful option in treatment of lacrimal duct obstruction.
OBJECTIVE: To evaluate the clinical efficacy and safety of polyurethane nasolacrimal duct stents in patients with nasolacrimal duct obstruction.
METHODS: Between 2008 and 2009, we treated 94 consecutive nasolacrimal obstructions in 87 patients (mean age 56 years; range 26-71 years) with implantation of polyurethane stents. Indications were nasolacrimal duct obstruction in 31 patients and chronic dacryocystitis in 56 patients. Follow-up was 18 months.
RESULTS AND CONCLUSION: On day 2 after implantation, resolution of epiphora was complete in 92 eyes, accounting for 98% success rate (92/94). On follow-up, 85 of 94 stents (90%) remained patent. There were eight cases developing stent obstruction. Stents malfunctioned in one case, and was easily withdrawn. Complications included pain in seven cases, eyelid inflammation in two cases and nasal hyporrhea in all cases. Experimental findings indicate that polyurethane nasolacrimal duct stent is a quick and useful option in treatment of lacrimal duct obstruction.

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